Journey of Mefenamic Acid

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1950s

Fenamates developed as anti-inflammatory agents

1962

Mefenamic acid released for pharmaceutical purposes.

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1980s

In India, mefenamic acid became available as MEFTAL

1990s

Mefenamic Acid (MEFTAL) reported to be among the top 3 NSAIDS prescribed

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2021

Mefenamic acid repurposed for management of fever in COVID-19 (off-label)

Increased use through Doctor Prescriptions

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Patient's Corner

All about Fever

Fever is an acute condition, and needs proper care and suitable treatment. Moderate to high fever can make you uncomfortable and can be a sign of an underlying serious illness or disease.

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HCP Corner

Red Flags in Fever

Prostration unable to stand, sit, or walk without help.

Temperature Hyperpyrexia (>106.7°F) or hypothermia (temperature <96.8°F) or rigors

Respiration Shortness of breath, respiratory rate >22 breaths/ minute, cyanosis, arterial oxygen saturation <92% on room air

Circulation Blood pressure <100 mm Hg systolic, cold, clammy extremities, capillary refill>3 seconds.

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FAQs

  • Oral temperature of 100°F or higher
  • Armpit temperature of 99°F or higher.

Viruses cause most fever incidences. A much smaller number are due to bacterial infections

Use a thermometer for fever measurement.

Consult the Doctor and administer the appropriate medications as prescribed.

Dress in lightweight clothes. Shivering may be a sign that your fever is rising. Do not put extra blankets or clothes on, as it may cause the fever to rise even higher.

A high fever needs immediate attention. Call the Doctor if body temperature is 102°F or higher.

No, teething does not cause fever. However, children who are teething may start to put things in their mouths to chew on which may lead to infection and fever.

In most cases, vaccination may cause fever. A fever with immunization is a sign indicating that the body is responding to the vaccine.

Children between six months and six year old may experience febrile fits or seizures if the fever is continuously high. It is characterized by losing consciousness and shaking or jerking arms and legs.

If the child has a febrile seizure, one should stay calm and:

  • Gently place the child on the floor or the ground.
  • Remove any nearby objects.
  • Place the child on his or her side to prevent choking.
  • Loosen any clothing around the head and neck.
  • Watch for signs of breathing problems, including bluish color on the face.
  • Take your child to the hospital immediately.

A drop in body temperature below 97.7.0 °F is hypothermia. If there is prolonged exposure to cold, the temperature can further drop below which should be attended immediately.

Newborns, infants, and young children are more likely to develop hypothermia because they have a larger surface area than body weight; therefore, they can lose body heat faster than older children and adults

The common symptoms of hypothermia include shivering, pale, cold, and dry skin, skin and lips may become blue, slurred speech, slow breathing, tiredness, or confusion. A child with hypothermia may be:

  • Cold to touch, and their skin may be red.
  • Floppy
  • Unusually quiet and sleepy and may refuse to feed

  • Move the child indoors or somewhere sheltered as quickly as possible.
  • Remove any wet clothing, and wrap them in a blanket,
  • Give them a warm drink and some sugary food like chocolate if they're fully awake
  • Do not use a hot bath, hot water bottle, or heat lamp to warm them up
  • Do not rub their arms, legs, feet, or hands